Shop

Description

What is Nalcip 50 Tablet?

Nalcip 50 Tablet is a generic drug of Naltrexone used to cure opioid dependence and alcohol dependence. It is used as a prevention method in case of drug abuse and also has a unique role in alcohol addiction.

Naltrexone Hydrochloride is a pure opioid antagonist — a synthetic congener of oxymorphone with no opioid agonist properties. It blocks the impact of opioids by competitive binding at opioid receptors.  This means Nalcip 50 removes the “reward” that drives addictive behaviour — without creating any dependence or addiction of its own.

Nalcip 50 Tablet is manufactured by Intas Pharmaceuticals Ltd., a globally recognized pharmaceutical company.  It is trusted by doctors across India and exported worldwide including to Australia, UK, France, USA, and China.

Uses & Indications

Nalcip 50 Tablet is medically prescribed for:

• Alcohol Use Disorder (AUD) — helps people lessen their drinking behaviours and avoid relapses. Over time, cravings for alcohol decrease significantly.
• Opioid Use Disorder (OUD) — prevents euphoria and reduces physiological dependence on opioids such as heroin, morphine, and codeine, helping people avoid relapses and remain in recovery programmes.
• Relapse Prevention — maintaining long-term abstinence from opioids and alcohol after successful detoxification
• Comprehensive De-Addiction Programme — used alongside counselling, psychotherapy, and behavioural intervention for complete recovery support

Nalcip 50 is for use as an additional therapy within a comprehensive treatment programme including psychological guidance for detoxified patients who have been opioid-dependent.  It is not a standalone cure for addiction.

Dosage & How to Take

For Alcohol Use Disorder: The recommended dose is one tablet (50mg) once daily. MedlinePlus

For Opioid Use Disorder: Start with half a tablet (25mg). If no withdrawal signs occur, increase the dose to one tablet (50mg) per day from then on. MedlinePlus

Alternative Dosing Schedule (for compliance): The dosage regimen can be modified to a three-times-a-week dosing schedule: two tablets (100mg) on Monday and Wednesday, and three tablets (150mg) on Friday. A dose of over 150mg on any single day is not recommended, as this can lead to a higher incidence of side effects.

How to Take:

1. Take Nalcip 50 with or without food. Take it regularly at a fixed time each day to get maximum benefit.
2. Nalcip 50 tablets should be swallowed whole with a liquid.  Do not crush, break, or chew.
3. Continue taking the medicine for as long as the doctor has prescribed it. Do not stop taking it until you have finished the full course.
4. Treatment with Nalcip must not be started before confirming the patient has remained opioid-free for a minimum of 7–10 days, confirmed by urine screening.
5. Treatment must begin with low doses of Naltrexone, according to the treatment induction schedule — the recommended initial dose is 25mg (half a tablet) followed by 50mg per day (one tablet).

Always follow the dosage and schedule prescribed by your doctor exactly. Never self-medicate or adjust the dose without medical guidance.

How Does Nalcip 50 Work?

Naltrexone works by blocking the effects of alcohol and opioid medications, preventing the euphoria and intoxication (the “buzz”) these substances cause. It also helps reduce the urge or cravings to use alcohol or opioids.

Naltrexone markedly attenuates or completely blocks, reversibly, the subjective effects of intravenously administered opioids. When co-administered with morphine on a chronic basis, Naltrexone blocks the physical dependence to morphine, heroin, and other opioids.

It enables the brain to stop the effect of opioid drugs — which includes extreme relaxation and other emotions that don’t result from the natural flow of the body. Thereby, the patient also develops the strength to cope with the temptation of opioid drugs, which will reduce day by day. It also has a unique role in alcohol addiction where, similarly, it reduces the urge for alcohol intake.

The administration of Naltrexone is not associated with the development of tolerance or dependence making it a completely safe, non-addictive medicine for long-term use as part of a recovery programme.

Key Benefits of Nalcip 50 Tablet

• FDA-approved opioid antagonist — globally trusted de-addiction medicine since 1984
• Dual-action — effective for both opioid dependence AND alcohol use disorder
• Blocks euphoric effects — removes the “high” that reinforces addictive behaviour
• Reduces and eliminates cravings over time with consistent use
• Non-addictive formula — the administration of Naltrexone is not associated with the development of tolerance or dependence
• Flexible dosing options — daily or three-times-a-week schedule for better compliance
• Manufactured by Intas Pharmaceuticals Ltd. — globally trusted Indian pharma company
• Affordable and widely exported — available in India, UK, USA, Australia, and more
• Supports long-term recovery — most effective when used with counselling and therapy

Precautions & Important Warnings

Before taking Nalcip 50, inform your doctor if you:

• Are currently using opioid medicines or have used them in the last 7–10 days
• Have liver disease, hepatitis, or elevated liver enzymes
• Have kidney disease
• Have a history of depression or other mental health conditions
• Are pregnant or planning to become pregnant
• Are currently breastfeeding
• Have a history of bleeding disorders or seizures

Critical Safety Warnings:

• Naltrexone administered to opioid-dependent persons can cause life-threatening withdrawal symptoms. Administration must not be started before a naloxone challenge test is performed and a negative result obtained.
• Treatment with Nalcip 50 should be considered only in patients who have remained opioid-free for a minimum of 7–10 days. Before starting treatment, this must be confirmed by urine screening.
• Nalcip 50 is contraindicated in patients with acute hepatitis or liver failure.
• Regular liver function tests (ALT, AST, gamma-glutamyltransferase, bilirubin) should be performed before treatment begins and at intervals thereafter — at 1, 3, and 6 months, then yearly.
• Do not drive or do anything requiring concentration until you know how Nalcip 50 affects you.
• Do not use any narcotics while using Nalcip 50 — it could lead to serious injury or damage if high doses of narcotics are taken alongside it.
• If you are an alcoholic and continue consumption of alcohol, do not take Nalcip 50.
• Naltrexone components are found in breast milk — do not continue taking it while breastfeeding without proper medical supervision.
• Naltrexone is not recommended in children and adolescents below 18 years of age.
• Carry written information with you at all times to alert healthcare providers that you are taking this medication so that they can treat you properly in an emergency  especially for situations requiring opioid pain relief (surgery, injury).

Drug Interactions

Inform your doctor if you are currently taking:

• Opioid medicines — morphine, codeine, tramadol, fentanyl, methadone — Nalcip will block their effects and may trigger severe withdrawal
• Buprenorphine — do not consume Naltrexone with Buprenorphine; watch for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce the efficacy of Buprenorphine.
• Opioid-containing cough syrups, cold medicines, or antidiarrheal drugs — check all OTC products carefully
• Disulfiram (Antabuse) — both affect liver function; requires close monitoring
• Antidepressants or antipsychotics — potential interaction affecting mood regulation
• Thioridazine — lethargy and drowsiness may increase significantly
• Herbal supplements or vitamins — always inform your doctor of all supplements

Side Effects

Nalcip 50 is generally well-tolerated. Common side effects include nausea, vomiting, headache, nervousness, anxiety, sleep disorders, restlessness, abdominal pain, joint pain, muscle pain, and weakness.

Common Side Effects (mild & usually temporary):

• Nausea or upset stomach
• Headache or dizziness
• Anxiety or nervousness
• Sleep disturbances or insomnia
• Restlessness or irritability
• Abdominal or stomach pain
• Joint or muscle pain
• Fatigue or weakness
• Loss of appetite

Serious Side Effects — Seek Immediate Medical Attention:

• Severe abdominal pain (upper right side) — possible liver complication
• Yellowing of skin or eyes (jaundice)
• Dark or cola-coloured urine
• Severe depression or thoughts of self-harm
• Severe allergic reaction — rash, swelling of face or throat, difficulty breathing
• Hallucinations or unusual mental changes
• Chest pain or irregular heartbeat
• Signs of opioid withdrawal — sweating, shivering, runny nose, muscle aches, vomiting

If you experience any serious side effects, stop taking Nalcip 50 immediately and seek emergency medical help without delay.

Missed Dose

A missed dose can be managed by providing one tablet per day until the next regular dosage administration. If your next dose is very close, skip the missed dose and continue with your normal schedule. Never double your dose to compensate for a missed one.

Storage Instructions

• Store at room temperature (15°C–30°C / 59°F–86°F), away from heat and direct sunlight.
• Keep in a cool, dry place protected from moisture and humidity.
• Store out of reach of children and pets.
• Keep in the original packaging — do not transfer to another container.
• Do not freeze.
• Check the expiry date before use. Safely dispose of expired or unused medicine through a medicine take-back programme.

Frequently Asked Questions (FAQ)

Q: What is Nalcip 50 used for?

A: Nalcip 50 is a prescription medication used to treat alcohol use disorder (AUD) and opioid use disorder (OUD) to reduce cravings and help control physiological dependence.

Q: How does Nalcip 50 reduce alcohol cravings?

A: For alcohol use disorder, Nalcip 50 helps people lessen their drinking behaviours and avoid relapses. Over time, cravings for alcohol will decrease.

Q: Is Nalcip 50 addictive?

A: No. The administration of Naltrexone is not associated with the development of tolerance or dependence. It has no euphoric effects and no abuse potential.

Q: How long before starting Nalcip 50 after stopping opioids?

A: Treatment should be considered only in patients who have remained opioid-free for a minimum of 7–10 days. This must be confirmed by urine screening before starting Nalcip 50.

Q: Can I drink alcohol while taking Nalcip 50?

A: Nalcip 50 blocks the feelings of intoxication (the “buzz”) from alcohol when you drink it. This allows people with alcohol use disorder to lessen their drinking behaviours enough to stay in treatment and avoid relapses. However, it does not prevent impairment  do not drink and drive.

Q: How long does treatment with Nalcip 50 last?

A: As Naltrexone is an adjunctive therapy and the full recovery process in opioid-dependent patients is individually variable, no standard duration of treatment can be stated. An initial period of three months should be considered. However, prolonged administration may be necessary.

Q: Can Nalcip 50 affect my liver?

A: Since Naltrexone is extensively metabolized by the liver and excreted predominantly in the urine, caution should be observed in administering the drug to patients with impaired hepatic or renal function. Liver function tests should be carried out both before and during treatment.

Q: Is a prescription required to buy Nalcip 50?

A: Yes. Nalcip 50 is a Schedule H prescription medicine. Please upload a valid doctor’s prescription at checkout.