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Description

What is Lodonak Tablet?

Lodonak is a doctor-prescribed medicine used to treat alcohol and opioid addictions by working on the chemical substances in the brain and decreasing the urge to take them.

Lodonak contains Naltrexone Hydrochloride, a medication used to help individuals who are recovering from opioid addiction. It works by blocking opioid receptors in the brain, reducing the effects and cravings for opiates, and preventing relapse.

Lodonak is produced by Kachhela Medex Pvt. Ltd., a manufacturer with experience creating both generic and specialty pharmaceuticals, providing high-quality, affordable pharmaceuticals to meet a range of patient needs.

Lodonak is available in low-dose formulations (LDN) — 1.5mg, 3mg, and 4.5mg — as well as standard doses, allowing doctors to tailor treatment based on each patient’s specific needs and recovery stage.

Uses & Indications

Lodonak Tablet is medically prescribed for:

• Opioid Use Disorder (OUD) — reduces cravings and dependence, helping the patient’s body and mind recover from consistent opioid dosing
• Alcohol Use Disorder (AUD) — reduces the urge to drink frequently and reverses the addiction to alcohol
• Relapse Prevention — helps maintain long-term abstinence from opioids and alcohol after detoxification
• Low Dose Naltrexone (LDN) Therapy — off-label use under medical supervision for autoimmune and chronic inflammatory conditions
• Weight Management Support — Naltrexone targets brain receptors that regulate appetite and food intake, reducing cravings for food (under medical guidance)

Lodonak is not a cure but forms a vital part of a comprehensive addiction treatment plan, including counselling, lifestyle changes, and compliance monitoring.It must always be used as part of a supervised medical programme.

Dosage & How to Take

Available Strengths:

• 1.5mg — Low Dose Naltrexone (LDN) — for autoimmune / off-label use
• 3mg — Low Dose Naltrexone (LDN) — mid-range LDN dose
• 4.5mg — Low Dose Naltrexone (LDN) — standard LDN protocol dose
• Standard Dose — as prescribed by your doctor for addiction treatment

How to Take:

1. Take Lodonak orally with or without food, once daily. Dosage may be adjusted by the physician depending on the treatment plan.
2. Swallow the tablet whole — do not crush, chew, or split.
3. Take it in the morning at the same time each day to help maintain a consistent level in the body.
4. Do not start until at least 7–10 days after the last opioid use — starting while opioids are still in your system can trigger sudden and severe withdrawal symptoms.
5. Follow the complete treatment program for optimal results.

Never self-prescribe or adjust your dose without consulting your doctor. Always follow the prescribed dosage schedule exactly.

How Does Lodonak Work?

Lodonak (Naltrexone) belongs to the antagonists group — it works by blocking the pleasurable sensation of opioids and alcohol, which eventually reduces the cravings.

In simple terms, when opioids or alcohol are consumed, they typically attach to opioid receptors in the brain, triggering feelings of euphoria and pleasure — the “reward” that reinforces addictive behaviour. Lodonak helps manage opioid and alcohol dependence by blocking euphoric effects, reducing cravings, and supporting long-term recovery from addiction.

For Low Dose Naltrexone (LDN) therapy — at doses of 1.5mg to 4.5mg — Naltrexone briefly blocks opioid receptors for a few hours, which causes the body to compensate by producing more of its own natural endorphins. This “rebound effect” may help modulate the immune system and reduce chronic inflammation, which is why LDN is being explored for various autoimmune conditions under medical supervision.

Key Benefits of Lodonak Tablet

• Clinically proven opioid antagonist — decades of global use for addiction treatment
• Reduces cravings for both opioids and alcohol effectively
• Blocks euphoric effects — removes the reward that drives addiction
• Supports long-term recovery and relapse prevention
• Non-addictive, non-opioid formula — Naltrexone itself has no abuse potential
• Available in multiple strengths — from 1.5mg LDN to standard therapeutic doses
• Improves mood and mental clarity when used as part of a recovery programme
• Affordable and accessible — manufactured by trusted Indian pharmaceutical company
• About one-third of alcoholics are reported to recover within a year with proper treatment support including Naltrexone

Precautions & Important Warnings

Before taking Lodonak, inform your doctor if you:

• Are currently using opioid medications (pain killers, methadone, buprenorphine)
• Have liver disease, hepatitis, or elevated liver enzymes
• Have kidney disease
• Have a history of depression or other mental health conditions
• Are pregnant or planning to become pregnant
• Are currently breastfeeding
• Have a history of bleeding disorders

Critical Safety Warnings:

• Must not be used if opioids are currently in the system  this will trigger sudden, severe opioid withdrawal (precipitated withdrawal), which can be medically dangerous.
• Begin only after 7–10 days of complete opioid abstinence.
• Regular liver function tests may be required during treatment Naltrexone can affect liver enzymes, particularly at higher doses.
• Avoid alcohol and sedatives during treatment.
• Not recommended for individuals with a history of seizures or eating disorders such as anorexia or bulimia.
• If you need emergency opioid pain relief during treatment (e.g., surgery), inform your medical team immediately — higher doses of opioids may be required, with careful monitoring.
• Not recommended during pregnancy unless advised by a healthcare provider.

Drug Interactions

Inform your doctor if you are currently taking:

• Opioid medicines — morphine, codeine, tramadol, fentanyl, methadone, buprenorphine — Naltrexone will block their effects and may trigger withdrawal
• Opioid-containing cough syrups or cold medicines — check all over-the-counter products carefully
• Antidepressants — may interact with the mood-regulatory effects of Naltrexone
• Thioridazine (antipsychotic) — lethargy and drowsiness may increase
• Disulfiram (Antabuse) — both medicines affect liver function; requires close monitoring
• Herbal supplements or vitamins — always inform your doctor of all supplements

Side Effects

Lodonak Tablet is generally well-tolerated, especially at low doses. Most side effects are mild and improve as the body adjusts.

Common Side Effects (mild & usually temporary):

• Sleep disturbances or insomnia
• Headache or dizziness
• Nausea or stomach upset
• Loss of appetite
• Fatigue or low energy
• Anxiety or restlessness
• Dry mouth

Serious Side Effects — Seek Immediate Medical Attention:

• Severe nausea and vomiting
• Stomach pain (especially upper right side — possible liver issue)
• Yellowing of skin or eyes (jaundice)
• Signs of depression or thoughts of self-harm
• Severe allergic reaction — rash, swelling, difficulty breathing
• Hallucinations or confusion
• Chest pain or irregular heartbeat

If you experience any serious side effects, stop taking Lodonak immediately and seek emergency medical help.

Missed Dose

The missed dose should be taken as soon as you remember. If your next dose is almost due, skip the missed one. Never take two tablets at once. Do not double your dose to compensate for a missed one.

Storage Instructions

• Store at room temperature between 20°C and 25°C.
• Keep in a cool, dry area away from moisture and direct sunlight.
• Keep out of reach of children and animals.
• Keep in original packaging. Do not freeze.
• Check the expiry date before use. Dispose of expired or unused medicine safely.

Frequently Asked Questions (FAQ)

Q: What is Lodonak used for?

A: Lodonak 3mg is used to treat alcohol addiction and opioid use disorder. It helps suppress the desire to dose on opiates and alcohol, letting patients recover their lifestyle physically, emotionally, mentally, and psychologically.

Q: How long do I need to take Lodonak?

A: Duration of treatment varies by individual and is determined by your doctor. It is typically used for several months as part of a comprehensive recovery programme including counselling and behavioural therapy.

Q: Can I drink alcohol while taking Lodonak?

A: No. You should avoid alcohol and sedatives during treatment. Naltrexone will block the pleasurable effects of alcohol, and drinking while on treatment can cause unpleasant reactions.

Q: Is Lodonak addictive?

A: No. Naltrexone itself does not cause physical or psychological dependence.  It is a non-opioid medicine with no abuse potential.

Q: What is Low Dose Naltrexone (LDN)?

A: Low Dose Naltrexone (LDN) in doses like 1.5mg is a low-dose formulation of Naltrexone Hydrochloride. In lower doses, it may also be explored for off-label use in autoimmune and chronic inflammatory conditions under medical supervision.

Q: How soon after stopping opioids can I start Lodonak?

A: You must not use Lodonak if opioids are currently in your system. Begin only after 7–10 days of complete opioid abstinence  to avoid precipitated withdrawal.

Q: Is a prescription required to buy Lodonak?

A: Yes. Lodonak is a Schedule H prescription medicine. Please upload a valid doctor’s prescription at checkout.