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Description

What is Zopisign Tablet?

Zopisign Tablet is a prescription-only sleeping medication that contains Zopiclone as its active ingredient. It belongs to a class of drugs called sedative-hypnotics, which work by slowing down activity in the brain to help you fall asleep faster and stay asleep longer.

Zopiclone helps reduce the amount of time it takes you to fall asleep (sleep latency), increases the amount of time you sleep (sleep duration), and decreases the number of times you wake up at night (nocturnal awakenings).

Zopisign is manufactured by HAB Pharmaceuticals & Research Ltd and is available in two strengths — 7.5mg (standard adult dose) and 10mg (higher dose for adults).

Uses & Indications

Zopisign Tablet is medically prescribed for the following sleep disorders:

• Sleep Onset Insomnia — Difficulty falling asleep at bedtime
• Sleep Maintenance Insomnia — Frequent waking during the night
• Early Morning Awakening — Waking too early and unable to fall back asleep
• Situational / Transient Insomnia — Caused by stress, travel, shift work, or temporary anxiety
• Short-Term Insomnia in adults where sleep problems are severe and disabling

Zopiclone is not recommended for long-term use (more than 4 weeks) for chronic insomnia because it may cause tolerance and dependence, leading to withdrawal and rebound insomnia if stopped suddenly.

Dosage & How to Take

Standard Adult Dose:

The recommended dose in adults is one zopiclone 7.5mg tablet just before bedtime.

For Elderly Patients (65+ years):

The usual starting dose in elderly patients is one low-strength tablet (3.75mg) or half a full-strength (7.5mg) tablet just before bedtime. The doctor may increase the dose to 7.5mg if needed.

Step-by-Step Instructions:

1. Take the tablet 30–60 minutes before bedtime on an empty stomach.
2. Swallow the tablet whole with a glass of plain water — do not crush or chew.
3. Only take this medication if you are able to get a full 7 to 8 hours of sleep before you need to be active again.
4. Do not take a second dose during the same night.
5. The usual length of treatment is 2 days to 3 weeks.

Always follow the dosage prescribed by your doctor. Do not self-medicate.

How Does Zopisign Work?

Zopiclone improves sleep by making a chemical in the brain called gamma-aminobutyric acid (GABA) more effective. GABA is a natural calming neurotransmitter that reduces brain activity, promoting feelings of relaxation and sleepiness.

Unlike older sleeping pills (benzodiazepines), Zopisign is a Z-drug (non-benzodiazepine) — meaning it works similarly but with a different chemical structure, and does not significantly alter sleep architecture, allowing for a more natural sleep pattern compared to some older sedatives.

Zopisign takes effect within 30–60 minutes after taking the tablet.

Key Benefits of Zopisign Tablet

• Falls asleep faster — reduces time taken to fall asleep
• Reduces nighttime awakenings — ensures longer, uninterrupted sleep
• Improves overall sleep quality — wake up feeling more rested
• Non-benzodiazepine formula — more natural sleep architecture
• Fast-acting — begins working within 1 hour
• Available in two strengths — 7.5mg and 10mg for flexible dosing
• Short-term relief — ideal for situational or stress-related insomnia

Precautions & Important Warnings

Before taking Zopisign, inform your doctor if you have:

• Liver or kidney disease
• History of drug or alcohol dependence
• Depression, anxiety, or other mental health conditions
• Breathing disorders or sleep apnea
• Myasthenia gravis (muscle weakness condition)
• History of sleepwalking

Critical Warnings:

• Do not drive within 12 hours of taking Zopisign Tablet — it can cause dizziness and impair your ability to drive or operate machines.
• Do not drink alcohol while taking Zopisign — alcohol can increase its effects and cause you to sleep very deeply, so that you do not breathe properly or have difficulty waking.
• Do not stop suddenly — stopping abruptly may cause withdrawal symptoms like anxiety, mood changes, and restlessness. Always taper under doctor’s supervision.
• Not for use during pregnancy or breastfeeding — may harm the unborn baby or nursing infant.
• Not suitable for children and adolescents under 18 years.
• Some people may experience sleepwalking or other unusual behaviors during sleep, including eating, having sex, or driving. Stop taking the medication immediately and contact your doctor if this happens.

Drug Interactions

Inform your doctor if you are taking:

• Opioid painkillers (codeine, morphine, tramadol) — increased sedation and breathing risk
• Antidepressants or antipsychotics — enhanced sedative effects
• Anti-epileptic drugs (phenytoin, carbamazepine) — altered effectiveness
• Antihistamines or other sedatives — risk of excessive drowsiness
• Antibiotics like Erythromycin — may increase Zopiclone levels in blood
• Caffeine — counteracts the sleep-inducing effects of Zopisign

Side Effects

Common Side Effects (usually mild and temporary):

• Mild bitter or metallic taste in the mouth, dry mouth, and feeling drowsy or sleepy
• Dizziness or light-headedness
• Headache
• Nausea or stomach upset
• Daytime drowsiness (especially in the morning)

Serious Side Effects — Seek Immediate Medical Attention:

• Memory loss or amnesia
• Confusion or disorientation
• Hallucinations or unusual behavioral changes
• Depression or worsening mood
• Difficulty breathing or chest tightness
• Severe allergic reaction (rash, swelling, difficulty breathing)

If you experience serious side effects, stop taking Zopisign and seek emergency medical help immediately.

Missed Dose

If you forget to take Zopisign by bedtime but remember during the night, only take the missed dose if you are still able to have 7 to 8 hours of uninterrupted sleep. If this is not possible, skip the missed dose and take your next dose before bedtime the next night as usual. Never double the dose.

Storage Instructions

• Store below 30°C away from heat and light. Do not store in the bathroom.
• Keep in a cool, dry place away from moisture and direct sunlight.
• Store out of reach of children and pets.
• Do not freeze.
• Check the expiry date before use and discard expired tablets safely.

Frequently Asked Questions (FAQ)

Q: How quickly does Zopisign Tablet work?

A: Zopisign starts working shortly after you take it. The maximum levels are reached within an hour of taking it.

Q: How long should I take Zopisign?

A: Treatment should be as short as possible and should not exceed four weeks, which includes the period of slowly decreasing the dose. For transient sleeplessness, the recommended duration is 2–5 days, and for short-lived sleeplessness, 2–3 weeks.

Q: Is Zopisign addictive?

A: You are unlikely to become addicted to zopiclone if you take it for up to 4 weeks. You may become dependent if you take it for longer than 4 weeks. Always use as prescribed.

Q: Can I take Zopisign with food?

A: Zopisign is best taken on an empty stomach just before bedtime for quicker absorption. However, it can also be taken after a light meal.

Q: Can Zopisign affect my memory?

A: Memory impairment is rare, but may occur, especially when sleep is interrupted or there is a delay in going to bed after taking the tablet. Patients should ensure they can have a full night’s sleep of about 7 to 8 uninterrupted hours.

Q: Is a prescription required to buy Zopisign?

A: Yes. Zopisign is a Schedule H prescription medicine. Please upload a valid doctor’s prescription at checkout.

Disclaimer: Zopisign is a Schedule H prescription medicine. The information provided here is for educational purposes only and does not substitute professional medical advice. Always consult a licensed healthcare provider before starting, stopping, or changing any medication.